CLAMOX LC

COMPOSITION

A syringe (3g) contains

Active substance

Amoxicillin 200 mg (as amoxicillin trihydrate)

Clavulanic acid 50 mg (as potassium clavulanate)

Prednisolone 10 mg                                 

TARGET SPECIES

Cattle (lactating cows)

INDICATIONS

For treatment in clinical cases of mastitis, including cases associated with infections caused by the following major pathogens:

Staphylococci (including beta-lactamase producing strains).

Streptococci (including S. agalactiae, S. Dysgalactiae and S. uberis).

Escherichia coli (including beta-lactamase producing strains).

CONTRAINDICATIONS

Do not use in animals with known hypersensitivity to beta-lactam antibiotics.

ADVERSE REACTIONS

None known.

DOSAGE FOR EACH SPECIES, METHOD AND ROUTE(S) OF ADMINISTRATION

The contents of a syringe should be infused into each affected quarter of the nipple and nipple sphincter, immediately after the complete quarter milking, every 12 hours for 3 consecutive milks. During treatment, clinical development should be evaluated by the veterinarian. In cases of infections caused by Staphylococcus aureus, a longer treatment period may be needed. Therefore, the total duration of treatment may be left to the decision of the veterinarian, but it must be long enough to ensure complete resolution of the bacterial disease.

WARNINGS/ADVICE ON CORRECT ADMINISTRATION

Before the infusion is performed, the nipple must be cleaned and disinfected.

WITHDRAWAL PERIOD(S)

Meat and offal: 7 days.

Milk: 84 hours. 

In cows milked twice a day, milk for human consumption can be given for consumption on the seventh milking after the last treatment. In the case of any other milking routine, milk may be used for human consumption only after the same period since the last treatment (e.g., for milks 3 times a day, milk may be given for human consumption on the 11th milking time).

SPECIAL PRECAUTIONS FOR STORAGE

Keep out of reach of children. Do not store above 25 °C. Keep in a dry place.

SPECIAL WARNING(S)

The product should only be used for the treatment of clinical mastitis.

The use of the product should be based on epidemiological information on the susceptibility of the target bacteria and respecting any official and local antimicrobial policies.

Avoid using the product in populations where strains of beta-lactamase-producing staphylococci have not been isolated. Inappropriate use of the product may increase the incidence of beta-lactam antibiotic-resistant bacteria and may decrease the effectiveness of beta-lactam antibiotic therapy due to their potential for cross-resistance

SPECIAL PRECAUTIONS TO BE TAKEN BY THE PERSON ADMINISTERING THE PRODUCT:

Penicillins and cephalosporins may produce hypersensitivity (allergy) reactions after self-injection, inhalation, ingestion or skin contact. Penicillin hypersensitivity may be associated with cross-sensitivity to cephalosporins and vice versa. Occasionally, the allergic reactions to these substances can be serious.

Do not handle this product if you know you are a person exhibiting sensitivity to it or have been warned not to handle such preparations.

Handle this product with great care to prevent exposure and take all precautions.

If symptoms occur following exposure to this product, such as itchiness, you should immediately see a doctor and present this warning. Swelling of the face, lips or eyes or difficulty breathing are more serious symptoms and require immediate medical attention. Wash your hands after using this product.

USE DURING PREGNANCY AND LACTATION 

No special precautions are required.

INTERACTION WITH OTHER MEDICINAL PRODUCTS AND OTHER FORMS OF INTERACTION

None known.

INCOMPATIBILITIES

In the absence of compatibility studies, this medicinal product will not be mixed with other veterinary medicinal products.

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCTS OR WASTE MATERIALS, IF ANY.

Any unused veterinary medicinal product or waste materials derived from such products should be disposed of in accordance with local requirements. Medicines should not be disposed of via waste water or household waste.

PRESENTATION/PACKAGE

White low-density polyethylene syringes.