COLISTOP PREMIX

COMPOSITION

Each gram of product contains 1000 mg of zinc oxide (active substance).

TARGET SPECIES

Piglets after weaning, from the age of 21 days to 10 weeks.

INDICATIONS

Prevention of post-weaning diarrhoea in piglets.

CONTRAINDICATIONS

None.

ADVERSE REACTIONS

By administering the medicated premix, piglet manure may become white to yellowish, but the situation returns to normal after cessation of treatment.

DOSAGE FOR EACH SPECIES, METHOD AND ROUTE(S) OF ADMINISTRATION

The medicated premix is ​​administered orally by incorporation into fodder. 

The recommended dose is 100 mg zinc oxide/kg body weight for 14 days.

Colistop Premix is ​​given to piglets from weaning (from the age of 21 days) to the age of 10 weeks.

Since the preventive treatment begins after weaning (21 days of age) and the average weight of the piglets is about 7 kg body weight with an average daily consumption of approximately 0.225 kg of fodder, the recommended dose of Colistop Premix in the final fodder is 3100 mg of Colistop Premix per kg of fodder (equivalent to 2500 mg zinc per kg of fodder). This dose corresponds to 3.1 kg of Colistop Premix per tonne of fodder.

WARNINGS/ADVICE ON CORRECT ADMINISTRATION

The amount of fodder ingested depends on the clinical condition of the animal so the fodder concentration must be adjusted to ensure proper dosing. Mix thoroughly to ensure homogeneous distribution of the premix in the fodder.

WITHDRAWAL PERIOD(S)

Meat and offal: 28 days.

SPECIAL PRECAUTIONS FOR STORAGE

This product does not require any special use conditions. Store in the original package. Do not use after the expiry date printed on the label. 

SHELF LIFE

Shelf life of the veterinary medicinal product as packaged for sale: 2 years. Shelf-life after first opening the immediate packaging: 28 days. Shelf-life after incorporation into fodder: 28 days.

SPECIAL PRECAUTIONS FOR EACH TARGET SPECIES

The administration of zinc-oxide medicated premix may alter certain biological parameters such as alkaline phosphatase, alpha-amylase activity, but these return to normal after discontinuation of therapy.

SPECIAL PRECAUTIONS FOR USE IN ANIMALS

Since zinc accumulates in the soil, it is recommended to rotate every two years the land on which the piglet manure is spread.

SPECIAL PRECAUTIONS TO BE TAKEN BY THE PERSON ADMINISTERING THE PRODUCT:

The veterinary medicinal product must not come into contact with the skin or mucous membranes and should not be inhaled. When mixing or handling fodder, a disposable mask shall be used in accordance with the EN 140, with EN 143 filter. In case of significant inhalation of dust or powder, leave the contaminated atmosphere and breathe fresh air; if the feeling of discomfort persists, contact your doctor.

When adding or handling the premix, use goggles and gloves. Avoid contact with skin and mucous membranes by using appropriate clothing. If skin contact occurs, wash affected area with soap and water.

If the veterinary medicinal product comes into contact with your eyes, rinse with plenty of water, and if irritation persists, contact your doctor. Contaminated clothing should be removed and washed before use. Wash your hands after use. In case of accidental ingestion, drink plenty of water and seek medical attention.

USE DURING PREGNANCY, LACTATION AND EGG-LAYING PERIOD

Not applicable.

INTERACTION WITH OTHER MEDICINAL PRODUCTS AND OTHER FORMS OF INTERACTION

Oral bioavailability of zinc may vary due to the ability of zinc ion to interact with other ions (calcium, copper, iron, cadmium)

OVERDOSE (SYMPTOMS, EMERGENCY PROCEDURES, ANTIDOTES)

No adverse reactions to this veterinary medicinal product have been observed in piglets given approximately double doses (200 mg zinc oxide/kg body weight/day) over a double administration period (28 days).

INCOMPATIBILITIES

In the absence of compatibility studies, this veterinary medicinal product shall not be mixed with other veterinary medicinal products.

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCTS OR WASTE MATERIALS, IF ANY

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements. Medicines should not be disposed of via waste water or household waste. The manufacturer recommends that the manure from the treated animals be handled and inactivated in accordance with the legislation in force to avoid contamination of the environment.

PRESENTATION/PACKAGE

25kg white propylene woven bags.