LEVAVERMIN

COMPOSITION

Each mL of product contains 50 mg of Levamisol (as hydrochloride)

TARGET SPECIES

Cattle, sheep, pigs and broilers

INDICATIONS

Levavermin 50 mg/mL is indicated for the treatment of endoparasite infections.

Cattle and sheep

Gastrointestinal nematodes: Trichostrongylus spp., Cooperia spp., Ostertagia ostertagi, Haemonchus spp., Nematodirus spp., Bunostomum spp., Oesophagostomum spp., Chabertia ovina.

Strongili pulmonari: Dictyocaulus viviparus.

Pigs

Gastrointestinal nematodes: Ascaris suum, Strongyloides ransomi, Oesophagostomum spp. Strongili pulmonari: Metastrongylus spp.

Broilers

Ascaridia spp., Heterakis spp., Capillaris spp.

CONTRAINDICATIONS

Do not use in cases of hypersensitivity to the active substance or to any of the excipients. Do not use if resistance to levamisole is suspected.

ADVERSE REACTIONS

Sometimes the following may appear: salivation, diarrhoea, restlessness and trembling.

DOSAGE FOR EACH SPECIES, METHOD AND ROUTE(S) OF ADMINISTRATION

Administer orally.

Cattle and sheep - 7.5 mg levamisole/kg body weight, a single administration equivalent to 0.15 mL Levavermin/kg body weight, without exceeding the total dose of 3.75 g levamisole (i.e., 75 mL Levavermin) in cattle and 0.375 g levamisole (7.5 mL Levavermin) in sheep.       Pigs - 7.5 mg levamisole/kg body weight, a single administration equivalent to 0.15 mL Levavermin/kg body weight, without exceeding the total dose of 0.75 g levamisole (i.e., 15 mL Levavermin).

Broilers - 20 mg levamisol/kg body weight, about 4 mL Levavermin per L of drinking water.

To ensure a correct dose, the body weight of the animals should be accurately determined, whenever possible, to avoid underdosing.

WARNINGS/ADVICE ON CORRECT ADMINISTRATION

The solution should be freshly prepared every 24 hours. No other source of water should be available during treatment. 

WITHDRAWAL PERIOD(S)

Meat and offal: 3 days

Use in animals producing milk for human consumption is not authorised.

Use in poultry laying eggs for human consumption is not authorised.

SPECIAL PRECAUTIONS FOR STORAGE

Keep out of reach of children. Do not store below 25°C. Do not refrigerate or freeze. Store in the original package. Store in a dry place. Keep away from direct light. Do not use after the expiry date printed on the label.

SHELF LIFE

Shelf life of the veterinary medicinal product as packaged for sale: 1 year. Shelf-life after first opening the original packaging: 28 days. Shelf-life after dilution in drinking water: 24 hours.

SPECIAL PRECAUTIONS FOR EACH TARGET SPECIES

Some precautions to avoid the following practices should be taken, because they may increase the risk of developing resistance and, implicitly, decreasing the inefficiency of treatment: too frequent and repeated use of antihelmintics in the same class over a prolonged period of time; underdosing, which may be due to an underestimation of body mass, misuse of the product or non-calibration of the dosing device (if any). All suspicious clinical cases of anthelmintic resistance should be further investigated using appropriate tests (e.g., OPG). Where tests clearly suggest resistance to a particular anthelmintic, another one shall be used, from a pharmacological class with a different mode of action.

SPECIAL PRECAUTIONS FOR USE IN ANIMALS

Not applicable.

SPECIAL PRECAUTIONS TO BE TAKEN BY THE PERSON ADMINISTERING THE PRODUCT:

Avoid skin contact. Wash your hands after use. When handling the product, wear suitable protective clothing, including waterproof rubber gloves. In case of accidental ingestion, seek medical advice immediately. Those with known hypersensitivity to levamisole should avoid contact with the veterinary medicinal product.

USE DURING PREGNANCY, LACTATION AND EGG-LAYING PERIOD

Studies in laboratory animals have revealed no potential teratogenic effect.

Studies in cattle, sheep and pig have revealed no embryotoxic or teratogenic potential.

The product can be used during gestation and lactation.

INTERACTION WITH OTHER MEDICINAL PRODUCTS AND OTHER FORMS OF INTERACTION

Concomitant administration of organophosphate insecticides may occasionally produce toxic reactions.

OVERDOSE (SYMPTOMS, EMERGENCY PROCEDURES, ANTIDOTES)

In the event of overdosage, the signs are those that result from stimulation of the parasympathetic nervous system: salivation, vomiting, diarrhoea, rapid breathing and ataxia, tremor, seizures. The antidotes used are atropine or glycopyrrolate.

INCOMPATIBILITIES

In the absence of compatibility studies, this veterinary medicinal product will not be mixed with other veterinary medicinal products.

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCTS OR WASTE MATERIALS, IF ANY

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with national requirements. Animals treated are kept in shelters throughout the treatment period and the resulting manure shall not be used for soil fertilisation.

PRESENTATION/PACKAGE

The product is packaged in while 50mL, 100mL, 250mL and 500mL HDPE vials and 1L, 5L, 10L, 20L HDPE cans.

HDPE threaded sealing caps.