EN
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CRIMECTIN INJ is effective for both prevention and treatment against the following endoparasites and ectoparasites:
Cattle: gastrointestinal roundworms (adult and larvae), lungworms (mature and fourth stage larvae), myiasis (all 3 stages larvae), lice, ticks.
Sheep and goats: gastrointestinal roundworms (adult and fourth stage larvae), lungworms (adult and fourth stage larvae), Dictyocaulus spp. (adult and fourth stage larvae), myiasis (all larvae stages); mites (Sarcoptes spp., Psoroptes spp.).
Pigs: gastrointestinal roundworms (adult and fourth stage larvae), lungworms (adult), lice, mites.
The use of the product in the target species should consider geographical difference in occurrence patterns of parasites.
Ivermectin 10 mg/ml
Do not administer by intramuscular or intravenous route.
Do not use in other species than those listed as severe adverse reactions, including fatalities in dogs, may occur.
Do not use in animals with known hypersensitivity to the active ingredient or excipients.
Transitory discomfort and a low inflammatory reaction have been observed at the injection site; these reactions disappear without treatment.
Destruction of migratory Hypoderma larvae in cattle, present in organs of vital importance, may cause undesirable "host-parasite” reactions not peculiar to ivermectin. If you notice any side effects, even those not already listed in this package leaflet, please inform your veterinary surgeon.
The product should be injected subcutaneously only.
Dosage:
Cattle, sheep and goats: 1 ml/50 kg bodyweight, equivalent to 0.2 mg ivermectin/kg bodyweight.
Pigs: 1 ml/ 33 kg bodyweight, equivalent to 0.3 mg ivermectin/kg bodyweight.
In young pigs, especially those below 16 kg bodyweight for which less than 0.5 ml of the product is indicated, dosing accuracy is important.
Normal aseptic precautions should be taken.
If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or overdosing.
Meat and offal:
Swine and goats: 28 days
Sheep: 21 days
Cattle: 49 days
Milk: Not permitted for use in lactating animals producing milk for human consumption.
Do not store above 25°C.
Do not refrigerate or freeze.
Store in the original container.
Store in a dry place.
Protect from direct sunlight.
Shelf-life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf-life after first opening the immediate packaging: 28 days.
Special warnings for each target species
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy.
- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
- Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the tests strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Special precautions for use in animals
Do not administer by intramuscular or intravenous route. Ivermectin is very effective against all stages of cattle grubs. However, proper timing of treatment is important. For the most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season.
Occasionally, the killed Hypoderma lineatum existing in periesophageal tissues may cause salivation and bloat. Similarly, killing Hypoderma bovis, if found in the vertebral canal, may cause unsteadiness or paralysis. Bovine should be treated before or after those stages of warble flies.
Special precautions to be taken by the person administering the medicinal products to the animals
People with known hypersensitivity to ivermectin, should avoid contact with product. Direct contact with skin and eyes should be avoided. If such contact occurs, rinse with plenty of water.
Do not smoke or eat while handling the product.
Take care to avoid self-administration: the product may cause local irritation and/or pain at the site of injection.
Use during pregnancy, lactation or lay
The product may be administered to dairy animals, during gestation or lactation, but the milk will not be given for human consumption.
Do not use in milking animals within 28 days prior to parturition in animals producing milk for human consumption.
Interaction with other medicinal products and other forms of interaction:
None known.
Overdose
Ivermectin is not toxic at up to 30-fold overdose. If suspected toxic reaction does occur due to overdosage, appropriate symptomatic treatment is recommended. Toxic symptoms caused by overdosage include tremors, convulsions and coma.
Incompatibilities
None known.
Vials: 50 ml, 100 ml, 250 ml and 500 ml.
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