FLORCRID 25 mg/ml

oral solution for pigs and chickens (broilers)

Indications

For the treatment of infections caused by florfenicol-susceptible bacteria, as follows:

In chickens (broilers): for the treatment and metaphylaxis of enteritis caused by Escherichia coli and of Chronic Respiratory Disease caused by Mycoplasma gallisepticum.

In pigs: for the treatment and metaphylaxis of swine respiratory diseases associated with Actinobacillus pleuropneumoniae and Pasteurella multocida.

COMPOSITION

Florfenicol         25 mg/ml

 

CONTRAINDICATIONS

Do not use in boars intended for breeding purposes.

Do not use in the case of known hypersensitivity to the active substance or to any of the excipients.

Do not use in piglets weighing less than 2 kg. 

 

ADVERSE REACTIONS

In pigs during treatment may notice a reduction in water consumption and occurrence following adverse reactions: erythema / edema perianal and rectal, transient diarrhea, constipation with stool dark brown. These reactions are transient and reversible.

 

DOSAGE FOR EACH SPECIES, ROUTE AND METHOD OF ADMINISTRATION

 

Oral administration via drinking water.

Chickens (broilers): 30 mg florfenicol/kg body weight/day, respectively 1,2 ml Florcrid/ kg body weight/day, for 3 consecutive days.

The amount of Florcrid solution (AFS) can be calculated based on total body weight of the herd to be treated (TBW) and the total water consumption of the herd in

24 hours (TWC) using the following formula:

 

CSF (L) = 30 x GCT (kg) 25 x CAT (L)

per 1000 liters of medicated water in the tank

If a dispenser set at P% percentage is used, the following formula is used:

 

CSF (L) = 30 x GCT (kg) 25 x CAT (L) x 1 P(%)

per 10 liters of pre-diluted medicated water in the dosing tank

 

Pigs: 10 mg florfenicol/kg body weight/day, respectively 0,4 ml Florcrid kg body weight/day, for 5 consecutive days.

The amount of Florcrid solution (AFS) can be calculated based on total body weight of the herd to be treated (TBW) and the total water consumption of the herd in

24 hours (TWC) using the following formula:

 

CSF (L) = 15 x GCT (kg) 25 x CAT (L)

per 1000 liters of medicated water in the tank

 

If a proportioner set at P% is used, then the formula is:

 

CSF (L) = 15 x GCT (kg) 25 x CAT (L) x 1 P(%)

per 10 liters of pre-diluted medicated water in the dosing tank.

 

ADVICE ON CORRECT ADMINISTRATION

To ensure correct dosage, body weight should be determined as accurately as possible to avoid underdosing. Ingestion of medicated water depends on the clinical

condition of the animals. Medicated water should be the only source of drinking water. Medicated drinking water should be prepared fresh every 24 hours.

If there is no improvement in clinical signs during treatment should review the diagnosis and the treatment should be changed.

WARNING !!!  

Solutions with a florfenicol concentration comprised between 1.2 g / liter and 12 g / liter precipitate. in cases of using a dispenser, if the AFS value appears from the calculations between 0.48 and 4.8, the percentage of dosage P (%) should be changed.

 

WITHDRAWAL PERIODS

Meat and offal:

Chickens (broilers): 3 days.

Pigs: 17 days.

 

SPECIAL STORAGE PRECAUTIONS

Keep out of the sight and reach of children. Do not store above 25°C. Do not refrigerate or freeze. Store in the original package. Store in a dry place. Protect from direct sunlight. Do not use this veterinary medicinal product after the expiry date which is stated on the label.

 

SHELF-LIFE

Shelf life after first opening the immediate packaging: 28 days.

Shelf life after reconstitution into drinking water: 24 hours.

Shelf life after reconstitution into drinking water: 24 h.

        

SPECIAL WARNINGS

Special precautions for use in animals

Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria. Use of the product deviating from the instructions given in the SPC may increase the prevalence of bacteria resistant to the active substance and may decrease the effectiveness of treatment due to potential of cross-resistance.

Official, national and regional antimicrobial policies should be taken into account when the product is used. The disease may determine a decreased water intake.  In case of insufficient intake of medicated water the treatment plan should be reviewed.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

Do not eat, drink or smoke whilst using the product.

People with known hypersensitivity to florfenicol or polyethylene glycol should avoid contact with the product. In case of accidental spillage into eyes, wash them immediately with water. In case of contact with skin, wash the affected area with water and soap immediately. In case of accidental ingestion, seek medical advice and show the physician the package leaflet.

Use during pregnancy, lactation or lay

Studies in laboratory animals have not revealed any evidence of embryo- or foeto-toxic potential for florfenicol. However, the effect of florfenicol to target

species reproductive performance and pregnancy has not been assessed.

Must not be used during pregnancy and lactation.

Interaction with other medicinal products and other forms of interaction

None known.

Overdose (symptoms, emergency procedures, antidotes), if necessary

In case of overdosage decreases water consumption, decreased weight gain, dehydration, edema anal / perianal, rectal prolapse, changes in hematological

and biochemical parameters.

Incompatibilities

In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.                  

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE MATERIALS, IF ANY 

Medicines should not be disposed of via wastewater or household waste.

Ask your veterinary or pharmacist how to dispose of medicines no longer required. These measures should help to protect the environment.

 

PRESENTATION/PACKAGE

HDPE white vials of 50 ml, 100 ml, 250 ml, 500 ml, 1000 ml and HDPE cans of 5 L, 10 L, 20 L.


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